Sanexon Injection Dosage & Drug Information

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Concise Prescribing Info

Contents

Methylprednisolone Na succinate

Indications/Uses

Abnormal adrenocorticoid function; allergic, collagen, dermatological, GI, haematological, ophth, resp, rheumatic disorders; hepatic, neurologic disease; hypercalcemia associated w/ neoplasm (or sarcoidosis), non-rheumatoid inflammation, nephrotic syndrome; neoplastic & resp diseases; neurotrauma: Spinal cord injury; pericarditis, nasal polyps, shock therapy caused by adrenocortical insufficiency, non-suppurative thyroiditis. Treatment of trichinosis. Prophylaxis & treatment of organ transplant rejection.

Dosage/Direction for Use

Adult IM/IV 10-40 mg, repeat as needed. Childn IM 139-835 mcg (0.139-0.835 mg)/kg 12-24 hrly. Adrenocortical insufficiency IM 117 mcg (0.117 mg)/kg in 3 divided doses every 3rd day.

Contraindications

Hypersensitivity. Systemic fungal infections, long-term use in patients w/ duodenal & peptic ulcer, severe osteoporosis, herpes; history of psychosis; recent immunization. Premature infant.

Special Precautions

Long-term use; patients should not be vaccinated against smallpox or other immune vaccines during therapy; latent TB or tuberculin reactivity; ocular herpes simplex. Pregnancy & lactation. Childn. Elderly.

Adverse Reactions

Adrenocortical insufficiency; musculoskeletal, ocular, endocrine, GIT, nervous system & dermatological effects, fluid & electrolyte disturbances. Sudden discontinuation produces nausea, vomiting, loss of appetite, lethargy, headache, fever, joint pain, desquamation, myalgia, wt loss, hypotension, hyper- or hypopigmentation, SC & cutaneous atrophy, sterile abscess, anaphylactic reaction, cardiac arrest, bronchospasm, cardiac arrhythmias.

View ADR Monitoring Form

Drug Interactions

Hepatic microsomal enzyme inducers, NSAIDs, K-depleting drugs, anticholinesterases, vaccines & toxoids.

MIMS Class

Corticosteroid Hormones

ATC Classification

H02AB04 - methylprednisolone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.

Regulatory Classification

Presentation/Packing

Form

Sanexon Injection 125 mg

Packing/Price

(vial) 2 mL x 1's (Rp98,550/boks)

Sanexon Injection

methylprednisolone

Manufacturer:

Sanbe